In 1917, on New York City’s Low­er East Side, Baruch Rosen­feld, fol­low­ing Jew­ish tra­di­tion, invites a beg­gar to join his fam­i­ly for the Passover Seder. Baruch is unaware that the beg­gar is actu­al­ly a mas­ter of tra­di­tion­al Jew­ish mag­ic who pun­ish­es the Rosen­felds by trap­ping them in a time bub­ble. The fam­i­ly doesn’t age, can’t leave their three-room apart­ment, and the out­side world believes they dis­ap­peared with­out a trace. 

A cen­tu­ry lat­er, the apart­ment build­ing is now the Ten­e­ment Muse­um. Esther Luna, a muse­um edu­ca­tor, sees Baruch’s young daugh­ter, Sadie, at the win­dow. Pre­sum­ing Sadie, a tres­pass­er, Esther goes to the apart­ment but finds it emp­ty. She hires Rab­bi Meir Pop­pers to solve the mys­tery of the girl at the win­dow. 

Pop­pers’ efforts to free the Rosen­felds are blocked by rivals, ancient spells, and his self-doubt. When he final­ly reach­es the trapped fam­i­ly, he must make deci­sions that will change their lives for­ev­er. Will Pop­pers’ own brand of Jew­ish mag­ic res­cue the Rosen­felds from their eter­nal prison?